1.
Ther Drug Monit
; 12(3): 281-3, 1990 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-2349613
RESUMO
Information is presented for the serum concentrations during haemodialysis of primidone, phenobarbitone, and phenylethylmalonamide (PEMA) in a patient with renal failure receiving chronic primidone therapy. The concentrations of drug and metabolites fell during haemodialysis, but PEMA concentrations were above normal at all times. The average renal clearance of PEMA during 6 h of dialysis was found to be 84.7 +/- 4.6 ml min-1.